A probabilistic method to detect regulatory modules
نویسندگان
چکیده
منابع مشابه
A probabilistic method to detect regulatory modules
MOTIVATION The discovery of cis-regulatory modules in metazoan genomes is crucial for understanding the connection between genes and organism diversity. RESULTS We develop a computational method that uses Hidden Markov Models and an Expectation Maximization algorithm to detect such modules, given the weight matrices of a set of transcription factors known to work together. Two novel features ...
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ژورنال
عنوان ژورنال: Bioinformatics
سال: 2003
ISSN: 1367-4803,1460-2059
DOI: 10.1093/bioinformatics/btg1040